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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328cf396ef8a6faf10c195170f5e20adf2faa2560153d22684cacd4f5efa3b6b' 
  AND token = 'BGNpqjzTlHNGMQWEIMXdO9ac+o1Wov0Bug1SVQyeWO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}