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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2180fbfa5bf421a972004677827fd144ee5b2f538f17e717144958cc4c77f992' 
  AND token = '61CQckTsHIAj+LfA1I5BSG8xdOrYyFlqJeEr8Gz+E6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}