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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292bb48b3e8aec181dc3dd0bdb6c7d59cc5d0ba3c59abe8f77787eecfd7bbcef' 
  AND token = '5DZxqKFG90V/FEZROkiGlJPjYTMcSU8dJ9vbGZz22Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}