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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c676505ee1ff9391439aef63479f561bb2fd2ac659c8e0836ac483a3fa5ea4a' 
  AND token = 'gMCFXiOOHfW4MsDtcRynZPUmpUp/BN/bdf7oyUE0rJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}