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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12db0aa2e8010a87dbb9ec8423369c3b802b9ddabe04e1fcf9a15d17215fa032' 
  AND token = '8w50rM7Wf+DsxsOaUl8xLLK4gS7iD6gxggVuPxfy59w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}