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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5377b06072dbcf37ae5b2f6281bcb68cbe930683be947283ffb1ffcb852afcc' 
  AND token = 'qc8fEqRoPNy+TyPGhY2TDynrH4N1AaQS7JmrA7wN8LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}