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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd3c90edc0d9cec1d0abe35927c492c47a0aa5795e1cf4deecdbebe94a59872' 
  AND token = 'R3k+UD3tuvD6MRNFRPm7sTJGw57I9W4AvRTVEkwo4K0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}