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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e78276a66bcbad1c0a9da50febc9bf7dfcf3ccbea35f858872e75f33b55b9f9' 
  AND token = 'NnxGRA4djxqw7Yi7XH6gy4W6r7UVnMafMlxyK9odT1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}