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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14edb5c4b5cbd37bb876888228e5403322c1df249e42b1971ebcf80f8a2bc88' 
  AND token = 'gN+ZAhCpOXVkqn1b6MgnzRHjVE5H1EtlpZvXNDgd9jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}