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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d81c0ab98bec0b82a10d8d85030585ba0e688c6f90585877b0393df87c785f' 
  AND token = 'uRMQszyyqf86QU5hrhze7hIs+UM4zdEEmcSNw7dc7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}