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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3db4fab7ed807ef1dc13b7b4612636ed3eef40c868140778d099e89a1ee0a3f' 
  AND token = 'lL3R4OH8EUvdrbNiCf3AlAOBk5ZEEXfMOTrplAFB9XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}