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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d74ea536b7a00b1a6ba6264231890293f1efb4a89c0507065af9c6d02b5c87' 
  AND token = '4F/hoLMK7n/Vhr9KVFmmhEyUFxc5bwqhw2DiQ/FRTxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}