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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3809c6d238f3799fbee2dd2271355f1598a1198a89530c65e964fcb01fff2d7' 
  AND token = '0YOYcaMhWsiUAxtF80Azegf06ekcZq9uDAmCzva7Hyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}