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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c251022b630d021cbf06b37af85b362d9c9b26233185b0a90cfa1d30ad0cbc37' 
  AND token = 'UJN6ci3xuaDysNRu9D/3EPKGGMIly70JK/JwVql5RVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}