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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b794ec414f9f21dbc47d92acfda29da3eff46ad5becd396e93db23556965df' 
  AND token = 'lutu0rBvyVL7/2RFILITzxxH1sgOcMZF7uQsoXyqhUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}