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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4887bf71e971e87cfd0edfde13257d86ca6c6db1d0539d19ebc25f74f7973e65' 
  AND token = 'FDot5RYSxrL9+xwKZuR3IFtfURnqzzfvJjwx0AwSSW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}