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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6955f35e31e67debeea2696c9131edb5e810ea529fc3626aa5d7a482e69940b5' 
  AND token = 'hO25u6iX1UcWzi7NJjt8DBDpV/QevpcOCRYl0kh3YnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}