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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac26ea0c64ad7ca86d8c897b15145a74ffe80db00cbe4972e5e729c5e2d510a2' 
  AND token = '1qn+cpyz5EaY79LHkCvvWBsnoSox+yTbLgRmwWAfPeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}