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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b825f81c61d422e2bcdf1336133aa0b95042c33dfe3b42a332e4e8fb99b043' 
  AND token = 'ZXWuGIoa/Qxb6GiUWI4JRHILx3RxpRBQXCzjYG+M0RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}