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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e86df023a5b1811fbaf9bd04f40bd81bb1550cc20a3d06cd2d32d2895c283477' 
  AND token = 'SHot8yM3f9lqYO1LwdpV9nlLUrXiRIvJRtDKDBSRheI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}