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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfea255f1456d31b2b8be57c2da5b7dd05bd935580e487876351d292a1c27c11' 
  AND token = 'symPvq3D4cAdRsgol7nRn2gM526NIg8NaN/E4SmZeAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}