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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ba08d33a758c4ac82c69ff1327c7f7fc5f52cb43a6ba478608b0d9098b5fa2' 
  AND token = '+URJbf41yhrmLM3icnLonXA7aUB49Sed8BIWc1iJdyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}