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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea21762782e71f4e59ab3d460fd62bf451d3f1b49b94ae7afec9aa7d40890a1a' 
  AND token = 'TxnudcTzIK1zeevZlXSR7NzkHn1kxWqi4y+vHg+XPYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}