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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b3d130f79c646db6521d2d6acef4eadb26ae031f4b785e6e3b401059ba7a365' 
  AND token = 'U4EkODCE/HpFuxWXYAO7YfxWk6kjJI2PqyeZPF1mpRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}