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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe65dc85a8ea0a1aa2dd6f1408ede308fe0afff332f250cd81a704f904cfd18' 
  AND token = '6V0T9P7JqDvQ+NmgZmnq5BxCBVpsGlid84KIDcsRvQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}