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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa20fc6f8e905886eb53cf5d26aa5e858bbdc2dea5a74ef2f68edecb057f6cdc' 
  AND token = 'tpYmvICOCId0qiW8CmH9zNtbNJt7srF2Ym4zS82xxaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}