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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b705d38b4a268c815470e797c64abf59dc585872a2c3541103c8e0bc262669' 
  AND token = 'FrF6dVQZvX53jfV0Z0YEv0CAZvtFsMXdyoW89WhvSSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}