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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c1fe9ad971d6889a36700a02714307506f1c9e1435c9b9de2f1e989748487e' 
  AND token = 'VPQgxm6Nk99idCW/l0QY0CPeSbw2OzpCXN6Der0AmuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00101

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}