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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f84a6a4a9f6eb1931d8cf9ce8201776ed9a89b809350d561449a4121872c18e8' 
  AND token = '1EzDwlYuDF0u4YxFa+tG4OywII2rwjdjkY5GGUNOhyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}