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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acfcde33d06aa08e203a2fd041a5b83277bde2881d70c40aa7150304300ff40d' 
  AND token = 'IGk59GTinTiWLn59FYIkKeQm4mdaMVqMp+5z6LvvjOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}