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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e58b5f6f5f46ab0ad2e2a8d781c4597e51386cdd8515612088f6dd3ceb62ee' 
  AND token = 'BRjboQoPZg7zsaoAlDVsuKwdjf3l2eIQx3rOTPtjhlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}