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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59429ab1b58764ac036d9c7f55276e452f007223fdd7c0a5cb1c8be6dd8a543f' 
  AND token = 'rev9FmdxN/rgk+xTAyNEZSutMft80AXDAU8WdZNIMro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}