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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb162b0612da45dfaa2aef4adf0602ef64509dc2cc15ca4474e6fd990b23a2c' 
  AND token = 'NXL6jtB6MXtD4obpB9/F/BSS64ElLVe9eqXxyP9gimg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}