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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '798196c6742ae0c0bfb5853375a2b7956186910fc306c2381ff13faf6f7c443c' 
  AND token = 'R1uRH/zD4j13r5nYNZGa1CuQUrCC0CEJSF/lAPSQs1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}