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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f029fce6b2832780a4b5ad40b97cc20e559914a482f1fc984035b79eceb196' 
  AND token = 'BPd/RqGwBd4Tv2DytRL55fveOlpaMwlh3zmriKD8yYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}