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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7021d08d8257b29286cc945cf2600ce445a0b2ab628cbd2f795968e9deb63bc7' 
  AND token = 'boyIYmL9YFd4kKH8c0Z5nN0T84EjW9HdoBYVulTpwTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}