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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21dbf1672b1925c36f43c6fc7f6fe2baf34b9ce56085a5e5ef631f42bd0337c7' 
  AND token = 'EQRAFEFHtIxGcJuaqKpsK9YFYJ+Ax5C6YPRHEW+91C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}