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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8dc15597eab5b626b6a0922b486a5d15e21a32415fde2b2d7bd39d41f3cf1c5' 
  AND token = 'tpVgnCZku9IYgrDb2kUct0rkuM/muLCfYdI194uytlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}