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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754edd7667640ccd8408ae05825cf4a956e7d0cb88cca9b44a7b873192871a8f' 
  AND token = 'jafagVsLxrOeiYXEljjBZW3KwAtfmdaDFv6AOMs2zTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}