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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7ceb79a22be5f13e3ecd11eb811d2df829d6b3459be00558fe1645089f60d7' 
  AND token = '3/E6tPZCm5LtL1t5luj6IY78XNu0wwF8v06jY/yG9AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}