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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5c9c12a62aa332d626902698a7cf256af0aae4fd7065b50f763950a8c0e0d7' 
  AND token = 'Sz8Ok22QDx4Ehrw5WDYoYMZGZ/lcZI/KbQmN+ywvbhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}