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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a6ac9b96b8db3765174e89de7bd072e89ec5f500c85b84eeed4df5a312e447' 
  AND token = 'EO+tvrFr3wfQe00Zb5HoUyn+ssG/l0Ik9Yp9kfU+T/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}