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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06451b8493383ed91b40ea71f00bfa852f02e1c9d222c1740ae3bea7f80544fd' 
  AND token = 'xPMSfNVU4UsWJijtevkwblriVRpC8NM9IZClLGMbnCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}