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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3aeb8b2b860a2e542bfbb4ed1f8134223514448679a5d9a217280ef482cc4b' 
  AND token = 'D18u/vexkKA9kuZxsPTXCexiIOFuPCVmQHR0xCf3Cp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}