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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246bd1ba00a0e4d6663d7e9828be9a7b5e762527bd3fa093f608142fec5617b6' 
  AND token = 'XYBb0EjtROVf3Y0n4oNi6E/ODhuNqfNilSuL+nFZclE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}