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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a7e6855b34ed21ccd8b786e0dab16d7f01dfc95a43adc81e70f1d2635263d8' 
  AND token = '5EVqy3rGhMiyzC2b0dnxBsmP1cpgnKrMvXn0J1pKlGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}