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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba35179ca297b4a9ea2367e1c0f4e9956bd98e4fcc5da5edc7b730471058283' 
  AND token = 'YFB73OE1T/uk7xdIQy3BatlFnY+vai2PvUAXSdUtK3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}