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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b553529b2af415c53350b1b495135325f016e06087e681acbe16d9f66c2e9f' 
  AND token = '9apld0stwSzeDoD1Xuyt7a61jab+7m1hVFHGZ17E22k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}