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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75166fe61b0d7c8216c7c6d0811a0633403478a96cc06bfc01b2cd23a6c91781' 
  AND token = 'Umm+FiJPpgoYXHJ699U03CrzZSy/ZZ+pTo8uHzuk1pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}