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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ba2950565a9361f04def50f3c18cc5ad68ec8377058553e257a6a91de972e92' 
  AND token = 'FVNvTFSnwPjF6eJnmPA/sqJd8v5FrOOASzPN+JfAz7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}